Temperature influences neuronal activity and CO2/pH sensitivity of locus coeruleus neurons in the bullfrog, Lithobates catesbeianus.

@article{Santin2013TemperatureIN,
  title={Temperature influences neuronal activity and CO2/pH sensitivity of locus coeruleus neurons in the bullfrog, Lithobates catesbeianus.},
  author={Joseph M Santin and Kayla C Watters and Robert W. Putnam and Lynn K Hartzler},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2013},
  volume={305 12},
  pages={R1451-64}
}
The locus coeruleus (LC) is a chemoreceptive brain stem region in anuran amphibians and contains neurons sensitive to physiological changes in CO2/pH. The ventilatory and central sensitivity to CO2/pH is proportional to the temperature in amphibians, i.e., sensitivity increases with increasing temperature. We hypothesized that LC neurons from bullfrogs, Lithobates catesbeianus, would increase CO2/pH sensitivity with increasing temperature and decrease CO2/pH sensitivity with decreasing… CONTINUE READING

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