Temperature-induced transitions in the structure and interfacial rheology of human meibum.

@article{Leiske2012TemperatureinducedTI,
  title={Temperature-induced transitions in the structure and interfacial rheology of human meibum.},
  author={Danielle L. Leiske and Christopher I. Leiske and Daniel R Leiske and Michael F Toney and Michelle Senchyna and Howard Allen London Ketelson and David N. Meadows and Gerald G. Fuller},
  journal={Biophysical journal},
  year={2012},
  volume={102 2},
  pages={
          369-76
        }
}
Meibomian lipids are the primary component of the lipid layer of the tear film. Composed primarily of a mixture of lipids, meibum exhibits a range of melt temperatures. Compositional changes that occur with disease may alter the temperature at which meibum melts. Here we explore how the mechanical properties and structure of meibum from healthy subjects depend on temperature. Interfacial films of meibum were highly viscoelastic at 17°C, but as the films were heated to 30°C the surface moduli… CONTINUE READING

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