Temperature enhances exocytosis efficiency at the mouse inner hair cell ribbon synapse.

@article{Nouvian2007TemperatureEE,
  title={Temperature enhances exocytosis efficiency at the mouse inner hair cell ribbon synapse.},
  author={R{\'e}gis Nouvian},
  journal={The Journal of physiology},
  year={2007},
  volume={584 Pt 2},
  pages={535-42}
}
Hearing relies on fast and sustained neurotransmitter release from inner hair cells (IHCs) onto the afferent auditory nerve fibres. The temperature dependence of Ca(2+) current and transmitter release at the IHCs ribbon synapse has not been investigated thus far. To assess the influence of temperature on calcium-triggered exocytosis, patch-clamp recordings of voltage-gated L-type Ca(2+) influx and exocytic membrane capacitance changes were performed at room (25 degrees C) and physiological (35… CONTINUE READING
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