Temperature dependent behavior of ultrasound contrast agents.

  title={Temperature dependent behavior of ultrasound contrast agents.},
  author={Helen Mulvana and Eleanor Stride and Jo V. Hajnal and Robert J. Eckersley},
  journal={Ultrasound in medicine & biology},
  volume={36 6},
Recent interest in ultrasound contrast agents (UCAs) as tools for quantitative imaging and therapy has increased the need for accurate characterization. Laboratory investigations are frequently undertaken in a water bath at room temperature; however, implications for in vivo applications are not presented. Acoustic investigation of a bulk suspension of SonoVue (Bracco Research, Geneva, Switzerland) was made in a water bath at temperatures of 20-45 degrees C. UCA characteristics were… CONTINUE READING