Temperature compensation in circadian clock models.

  title={Temperature compensation in circadian clock models.},
  author={Gen Kurosawa and Yoh Iwasa},
  journal={Journal of theoretical biology},
  volume={233 4},
Circadian clock of organisms has a free-running period that does not change much with ambient temperature. This property "temperature compensation" is studied when the rate of all reaction steps increase with temperature in the biochemical network generating the rhythm. The period becomes shorter when all the rate parameters are enhanced by the same factor. However, the period becomes longer as degradation rate of proteins and/or transcription rate of the clock gene increase (their elasticity… CONTINUE READING