Temperature‐dependent conformational transitions in poly(dG‐dC) and poly(dG‐m5dC)

@article{Behe1985TemperaturedependentCT,
  title={Temperature‐dependent conformational transitions in poly(dG‐dC) and poly(dG‐m5dC)},
  author={M. Behe and G. Felsenfeld and S. Szu and E. Charney},
  journal={Biopolymers},
  year={1985},
  volume={24}
}
The double‐stranded helical complexes of poly(dG‐dC) and of poly(dG‐m5dC) are shown to convert from B‐ to Z‐DNA‐type conformations at moderate or low ionic strengths, lower for the 5‐methyl than for the non‐methyl species, in a highly cooperative temperature‐dependent equilibrium. In the presence of low concentrations of divalent ion, e.g., Mg2+, the temperature at which the B → Z transition occurs is virtually independent of the salt concentration and the B‐conformation is favored at lower… Expand
59 Citations
Thermodynamics of the B to Z transition in poly(dGdC)
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