Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo.

@article{Bruyre2011TemozolomideMC,
  title={Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo.},
  author={C{\'e}line Bruy{\`e}re and Laurence Abeloos and Delphine Lamoral-Theys and Rebecca Senetta and V{\'e}ronique Mathieu and Marie Le Mercier and Richard Eric Kast and Paola Cassoni and Guy Vandenbussche and R{\'o}bert Kiss and Florence Lefranc},
  journal={Translational oncology},
  year={2011},
  volume={4 2},
  pages={92-100}
}
BACKGROUND Caveolin-1 is a protein that displays promotive versus preventive roles in cancer progression according to circumstances. Temozolomide (TMZ) is the standard chemotherapeutic to treat glioma patients. The present work aims to characterizeTMZ-induced effects on caveolin-1 expression in glioma cells. METHODS Human astroglioma (U373 and T98G) and… CONTINUE READING