Telomeric strategies: means to an end.

@article{Jain2010TelomericSM,
  title={Telomeric strategies: means to an end.},
  author={Devanshi Jain and Julia Promisel Cooper},
  journal={Annual review of genetics},
  year={2010},
  volume={44},
  pages={243-69}
}
What really defines a telomere? Telomere literally is an amalgamation of the Greek words "telos," meaning end, and "mer," meaning part. In practice, it refers to the extremities of linear chromosomes. The defining functions of chromosome extremities can be summarized in two main categories. First, chromosome ends trick the cell into not identifying them as damage-induced double-strand DNA breaks (DSBs). An internal DSB immediately triggers cell-cycle arrest and is repaired to ensure that genome… CONTINUE READING

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