Telomeric organization of a variable and inducible toxin gene family in the ancient eukaryote Giardia duodenalis.

@article{Upcroft1997TelomericOO,
  title={Telomeric organization of a variable and inducible toxin gene family in the ancient eukaryote Giardia duodenalis.},
  author={P. Upcroft and Nanhua Chen and J. A. Upcroft},
  journal={Genome research},
  year={1997},
  volume={7 1},
  pages={37-46}
}
Giardia duodenalis is the best-characterized example of the most ancient eukaryotes, which are primitively amitochondrial and anaerobic. The surface of Giardia is coated with cysteine-rich proteins. One family of these proteins, CRP136, varies among isolates and upon environmental stress. A repeat region within the CRP136 family is interchangeable by a cassette-like mechanism, generating further diversity in repeat size, copy number, and sequence. Flanking the 5' region of the CRP136 family is… CONTINUE READING

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