Telomeric noncoding RNA: telomeric repeat‐containing RNA in telomere biology

@article{Cusanelli2014TelomericNR,
  title={Telomeric noncoding RNA: telomeric repeat‐containing RNA in telomere biology},
  author={E. Cusanelli and P. Chartrand},
  journal={Wiley Interdisciplinary Reviews: RNA},
  year={2014},
  volume={5}
}
Telomeres are nucleoprotein structures that cap the ends of eukaryotic chromosomes, protecting them from degradation and activation of DNA damage response. For this reason, functional telomeres are vital to genome stability. For years, telomeres were assumed to be transcriptionally silent, because of their heterochromatic state. It was only recently shown that, in several organisms, telomeres are transcribed, giving rise to a long noncoding RNA (lncRNA) called telomeric repeat‐containing RNA… Expand
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