Telomeric DNA sequence and structure following de novo telomere synthesis in Euplotes crassus.

@article{Vermeesch1994TelomericDS,
  title={Telomeric DNA sequence and structure following de novo telomere synthesis in Euplotes crassus.},
  author={Joris Robert Vermeesch and Carolyn M. Price},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 1},
  pages={554-66}
}
To learn more about the mechanism of de novo telomere synthesis, we have characterized the sequence and structure of newly synthesized telomeres from Euplotes crassus. E. crassus is a particularly useful organism for studying telomere synthesis because millions of telomeres are made in each cell at a well-defined time during the sexual stage of the life cycle. These newly synthesized telomeres are approximately 50 bp longer than mature macronuclear telomeres. We have investigated the structure… CONTINUE READING