Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma

@inproceedings{Ventura2019TelomeresAT,
  title={Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma},
  author={A Ventura and Cristina Pellegrini and Ludovica Cardelli and Tea Rocco and Valeria Ciciarelli and Ketty Peris and Maria Concetta Fargnoli},
  booktitle={International journal of molecular sciences},
  year={2019}
}
The role of telomere biology and telomerase activation in skin cancers has been investigated in melanoma and basal cell carcinoma but limited evidence is available for cutaneous squamous cell carcinoma (cSCC). We will review the current knowledge on the role of telomere and telomerase pathway in cSCC pathogenesis. At the somatic level, both long and short telomere lengths have been described in cSCC. This telomere dichotomy is probably related to two different mechanisms of tumour initiation… CONTINUE READING

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