Telomeres, sex, reactive oxygen species, and human cardiovascular aging

@article{Aviv2002TelomeresSR,
  title={Telomeres, sex, reactive oxygen species, and human cardiovascular aging},
  author={Abraham Aviv},
  journal={Journal of Molecular Medicine},
  year={2002},
  volume={80},
  pages={689-695}
}
By undergoing erosion with each replicative cycle, telomeres chronicle the replicative history of human somatic cells in vitro and in vivo. In human beings the telomere is relatively short, inversely correlated with age, highly heritable, and longer in women than men. However, it is not established whether the dynamics of telomere attrition in vivo has a role in the biology of human aging. Telomere attrition may be modified by reactive oxygen species, the biology of which is governed by… CONTINUE READING