Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study.

@article{OCallaghan2014TelomereSI,
  title={Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study.},
  author={Nathan J. O’Callaghan and Natalie Parletta and Catherine M. Milte and Bianca Benassi-Evans and Michael Fenech and Peter R. C. Howe},
  journal={Nutrition},
  year={2014},
  volume={30 4},
  pages={
          489-91
        }
}
  • Nathan J. O’Callaghan, Natalie Parletta, +3 authors Peter R. C. Howe
  • Published in Nutrition 2014
  • Medicine
  • OBJECTIVES Excessive shortening of the telomeric ends of chromosomes is a marker of accelerated aging. Oxidative stress and nutritional deficiency may influence this process. The aim of this study was to investigate the effect of ω-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on telomeric shortening in elderly individuals with mild cognitive impairment (MCI). METHODS Thirty-three adults ages > 65 y with MCI were randomized to receive a supplement rich in the long-chain ω-3 PUFAs… CONTINUE READING

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