Telomere length variations in aging and age-related diseases.

  title={Telomere length variations in aging and age-related diseases.},
  author={S. Nishat Fatima Rizvi and Syed Tasleem Raza and Farzana Mahdi},
  journal={Current aging science},
  volume={7 3},
Telomeres are gene sequences present at chromosomal ends and are responsible for maintaining genome integrity. Telomere length is maximum at birth and decreases progressively with advancing age and thus is considered as a biomarker of chronological aging. This age associated decrease in the length of telomere is linked to various ageing associated diseases like diabetes, hypertension, Alzheimer's disease, cancer etc. and their associated complications. Telomere length is a result of combined… CONTINUE READING
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