Telomere length is paternally inherited and is associated with parental lifespan.

@article{Njajou2007TelomereLI,
  title={Telomere length is paternally inherited and is associated with parental lifespan.},
  author={Omer T. Njajou and Richard M. Cawthon and Coleen Mae Damcott and Shih-Hsuan Wu and Sandy Ott and Michael J Garant and Elizabeth H Blackburn and Braxton D. Mitchell and Alan R. Shuldiner and Wen Chi Hsueh},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 29},
  pages={
          12135-9
        }
}
Telomere length (TL) is emerging as a biomarker for aging and survival. To evaluate factors influencing this trait, we measured TL in a large homogeneous population, estimated the heritability (h(2)), and tested for parental effects on TL variation. Our sample included 356 men and 551 women, aged 18-92 years, from large Amish families. Mean TL in leukocytes was measured by quantitative PCR (mean: 6,198 +/- 1,696 bp). The h(2) of TL was 0.44 +/- 0.06 (P < 0.001), after adjusting for age, sex… CONTINUE READING

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