Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.

Abstract

The Ku70/80 heterodimer is a critical component of the non-homologous end-joining (NHEJ) pathway and of the telomere cap in yeast and mammals. We report the molecular characterization of the KU70 and KU80 genes in Arabidopsis and describe the consequences of a Ku70 deficiency. Arabidopsis KU70/80 genes are ubiquitously expressed and their products form… (More)

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@article{Rha2002TelomereLD, title={Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.}, author={Karel R{\'i}ha and J. Matthew Watson and Jeffrey S. Parkey and Dorothy E Shippen}, journal={The EMBO journal}, year={2002}, volume={21 11}, pages={2819-26} }