Telomere length behaves as biomarker of somatic redundancy rather than biological age.

@article{Boonekamp2013TelomereLB,
  title={Telomere length behaves as biomarker of somatic redundancy rather than biological age.},
  author={Jelle J Boonekamp and Mirre J P Simons and Lia Hemerik and Simon Verhulst},
  journal={Aging cell},
  year={2013},
  volume={12 2},
  pages={330-2}
}
Biomarkers of aging are essential to predict mortality and aging-related diseases. Paradoxically, age itself imposes a limitation on the use of known biomarkers of aging because their associations with mortality generally diminish with age. How this pattern arises is, however, not understood. With meta-analysis we show that human leucocyte telomere length (TL) predicts mortality, and that this mortality association diminishes with age, as found for other biomarkers of aging. Subsequently, we… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 14 times over the past 90 days. VIEW TWEETS