Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging.

@article{Roberts2014TelomereLA,
  title={Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging.},
  author={Jason D Roberts and Thomas A. Dewland and James Longoria and Annette L. Fitzpatrick and Elad Ziv and Donglei Hu and Jue Lin and David V. Glidden and Bruce M. Psaty and Esteban Gonz{\`a}lez Burchard and Elizabeth H Blackburn and Jeffrey E. Olgin and Susan R. Heckbert and Gregory M. Marcus},
  journal={Circulation. Arrhythmia and electrophysiology},
  year={2014},
  volume={7 6},
  pages={1026-32}
}
BACKGROUND Advanced age is the most important risk factor for atrial fibrillation (AF); however, the mechanism remains unknown. Telomeres, regions of DNA that shorten with cell division, are considered reliable markers of biological aging. We sought to examine the association between leukocyte telomere length (LTL) and incident AF in a large population-based cohort using direct LTL measurements and genetic data. To further explore our findings, we compared atrial cell telomere length and LTL in… CONTINUE READING
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by gest on A ril 6, 2017 http://cirhajournals.org/ D ow nladed from DOI: 10.1161/CIRCEP.114.001781

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