Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936

@article{Harris2012TelomereLA,
  title={Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936},
  author={S. Harris and C. Martin-Ruiz and T. Zglinicki and J. Starr and I. Deary},
  journal={Neurobiology of Aging},
  year={2012},
  volume={33},
  pages={1486.e3-1486.e8}
}
  • S. Harris, C. Martin-Ruiz, +2 authors I. Deary
  • Published 2012
  • Biology, Medicine
  • Neurobiology of Aging
  • Telomeres are nucleo-protein complexes at the end of eukaryotic chromosomes. They shorten each time a somatic cell replicates and this shortening is modulated by the effects of oxidative stress. Previous studies have associated telomere length with a number of age-related outcomes and it is hypothesized to be a quantitative indicator of aging. We tested this hypothesis in a cohort of ∼1000 relatively healthy 70-year-old Scots (the Lothian Birth Cohort of 1936: LBC1936) on whom we have measures… CONTINUE READING

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