Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility.

@article{ReigViader2014TelomereHI,
  title={Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility.},
  author={Rita Reig-Viader and Laia Capilla and Marta Vila-Cejudo and Ferran Mart{\'i}nez Garc{\'i}a and Bego{\~n}a Anguita and Montserrat Garcia-Cald{\'e}s and Aurora Ruiz-Herrera},
  journal={Fertility and sterility},
  year={2014},
  volume={102 3},
  pages={
          728-738.e1
        }
}
OBJECTIVE To study whether the telomere structure of germ cells from idiopathic infertile men is altered and if this impairment is influenced by meiotic recombination and telomere length. DESIGN We performed a detailed analysis of both telomeric repeat-containing RNA (TERRA) and telomerase distribution in testis cell spreads by combining immunofluorescence and RNA fluorescent in situ hybridization. In addition we analyzed meiotic recombination between homologous chromosomes by… CONTINUE READING
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