Telomere attrition and decreased fetuin-A levels indicate accelerated biological aging and are implicated in the pathogenesis of colorectal cancer.

@article{Maxwell2011TelomereAA,
  title={Telomere attrition and decreased fetuin-A levels indicate accelerated biological aging and are implicated in the pathogenesis of colorectal cancer.},
  author={Fraser Maxwell and Liane Mcglynn and Hannah C Muir and Dinesh K Talwar and Michaela Benzeval and Tony Robertson and Campbell S. D. Roxburgh and Donald Calum McMillan and Paul G. Horgan and Paul Gerard Shiels},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2011},
  volume={17 17},
  pages={5573-81}
}
PURPOSE Increasing chronological age is a risk factor for many types of cancer including colorectal. An understanding of the biology of aging and factors which regulate it may provide insight into cancer pathogenesis. The role of telomere biology in both the cancer and aging process could prove useful in this regard. EXPERIMENTAL DESIGN Using quantitative… CONTINUE READING