Telomere Length in the Newborn

@article{Okuda2002TelomereLI,
  title={Telomere Length in the Newborn},
  author={Koji Okuda and Arlene D. Bardeguez and Jeffrey P. Gardner and Paulette Rodriguez and Vijaya L. Ganesh and Masayuki Kimura and Joan H. Skurnick and Girgis Awad and Abraham Aviv},
  journal={Pediatric Research},
  year={2002},
  volume={52},
  pages={377-381}
}
Telomere length is similar in different organs of the human fetus but variable among fetuses. During extrauterine life telomere length is highly variable among individuals and longer in women than men. In the present work we addressed the following questions:1) Are there sex-related differences in telomere length at birth? 2) Is there synchrony (i.e. correlation in length) of telomeres in tissues within the newborn? 3) Is the variability in telomere length among newborns as large as that in… 

Figures and Tables from this paper

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The effect of intrauterine growth on leukocyte telomere length at birth
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  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
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Telomere length in early childhood is associated with sex and ethnicity
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The data suggest that telomere lengths are highly variable and variability between individuals arise from early age, influenced partly by sex and ethnicity, and may reflect the heritability of telomeres in genetically less complex populations.
Prenatal stress and newborn telomere length.
Sex difference in leukocyte telomere length is ablated in opposite-sex co-twins
TLDR
It is suggested that the sex difference in LTL, seen in the general population, is largely determined in utero, perhaps by the intrauterine hormonal environment.
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