Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms

@inproceedings{Raykov2016TelomereDT,
  title={Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms},
  author={Vasil Raykov and Marcus E. Marvin and Edward J Louis and Laura Maringele},
  booktitle={Genetics},
  year={2016}
}
Inverted chromosome duplications or palindromes are linked with genetic disorders and malignant transformation. They are considered by-products of DNA double-strand break (DSB) repair: the homologous recombination (HR) and the nonhomologous end joining (NHEJ). Palindromes near chromosome ends are often triggered by telomere losses. An important question is… CONTINUE READING