Telomere Dysfunction–Related Serological Markers Are Associated With Type 2 Diabetes

@inproceedings{Xiao2011TelomereDS,
  title={Telomere Dysfunction–Related Serological Markers Are Associated With Type 2 Diabetes},
  author={Feng Xiao and Xiaoguo Zheng and Mingming Cui and Guiying Shi and Xianda Chen and Ruili Li and Zhangfa Song and Karl Lenhard Rudolph and Bowen Chen and Zhenyu Ju},
  booktitle={Diabetes care},
  year={2011}
}
OBJECTIVE Recent studies have identified a set of serological markers for telomere dysfunction and DNA damage. The relevance of these serological markers in type 2 diabetes remains elusive. We investigated the association of serological markers (elongation factor 1α [EF-1α], stathmin, and N-acetyl-glucosaminidase) with leukocyte telomere length, a functional variant of uncoupling protein-2 (UCP2), and susceptibility of type 2 diabetes. RESEARCH DESIGN AND METHODS A total of 930 patients and… CONTINUE READING
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