Telomerase structure☆

  title={Telomerase structure☆},
  author={Sara Sandin and D. Rhodes},
  booktitle={Current opinion in structural biology},
The telomerase reverse transcriptase has an essential role in telomere maintenance and in cancer biology. Progress during the last year has revealed the three-dimensional architecture of both human and ciliate telomerase at about 25Å resolution, obtained using single particle electron microscopy (EM). The structural analysis of the two holoenzyme complexes… CONTINUE READING