Telomerase-specific oncolytic virotherapy for human gastrointestinal cancer.

Abstract

Replication-selective tumor-specific viruses present a novel approach for treatment of neoplastic disease. These vectors are designed to induce virus-mediated lysis of tumor cells after selective viral propagation within the tumor. Human telomerase is highly active in more than 85% of primary cancers, regardless of their tissue origins, and its activity… (More)
DOI: 10.1586/era.10.200

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Cite this paper

@article{Fujiwara2011TelomerasespecificOV, title={Telomerase-specific oncolytic virotherapy for human gastrointestinal cancer.}, author={Toshiyoshi Fujiwara and Yasuhiro Shirakawa and Shunsuke Kagawa}, journal={Expert review of anticancer therapy}, year={2011}, volume={11 4}, pages={525-32} }