Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized clinical trial.

@article{Paweczyk2018TelomeraseLI,
  title={Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized clinical trial.},
  author={Tomasz Paweł Pawełczyk and Marta Grancow-Grabka and Elżbieta Trafalska and Janusz Szemraj and Natalia Żurner and Agnieszka Pawełczyk},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={2018},
  volume={83},
  pages={142-148}
}
Schizophrenia is associated with shortening of the lifespan mainly due to cardiovascular events, cancer and chronic obstructive pulmonary disease. Both telomere attrition and decrease of telomerase levels were observed in schizophrenia. Polyunsaturated fatty acids (PUFA) influence multiple biochemical mechanisms which are postulated to accelerate telomere… CONTINUE READING