Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines.

Abstract

The knockdown of genes that are over-expressed in cancer, and function in tumor onset and/or progression, is an attractive tool to impair the growth of tumor cells. Synthetic nucleic acids such as antisense oligodeoxynucleotides (AS-ODNs) or small-interfering RNAs (siRNAs) were applied against different tumor-associated transcripts, including the human… (More)
DOI: 10.1007/978-1-60327-070-0_2

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