Telomerase and cancer.

@article{Shay2001TelomeraseAC,
  title={Telomerase and cancer.},
  author={Jerry W Shay and Ying Zou and Eiso Hiyama and Woodring E Wright},
  journal={Human molecular genetics},
  year={2001},
  volume={10 7},
  pages={677-85}
}
Telomerase, a eukaryotic ribonucleoprotein (RNP) complex, contains both an essential RNA and a protein reverse transcriptase subunit. By reverse transcription, the telomerase RNP maintains telomere length stability in almost all cancer cells. Over the past few years there has been significant progress in identifying the components of the telomerase holoenzyme complex and the proteins that associate with telomeres, in order to elucidate mechanisms of telomere length regulation. This review… CONTINUE READING

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