Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer.

@article{DettlaffPokora2005TelomeraseAI,
  title={Telomerase activity in urine sediments as a tool for noninvasive detection of bladder cancer.},
  author={Agnieszka Dettlaff-Pokora and Marcin Matuszewski and Beata Schlichtholz},
  journal={Cancer letters},
  year={2005},
  volume={222 1},
  pages={
          83-8
        }
}
Telomerase is extensively investigated as potential diagnostic and prognostic marker in human tumors. In this study, we determined telomerase activity in histological specimens and voided urine of 52 human bladder cancers. Using the PCR-ELISA method telomerase activity was found in 21 (88%) of the 24 tumor tissues and in the corresponding sediments from voided urine of patients with superficial bladder carcinoma (Ta/T1). In case of muscle-invasive tumors (T2-T4), telomerase activity was found… CONTINUE READING
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