Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.

@article{Kojima1997TelomeraseAA,
  title={Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.},
  author={Hiromi Kojima and Osamu Yokosuka and Fumio Imazeki and Hiromitsu Saisho and Masao Omata},
  journal={Gastroenterology},
  year={1997},
  volume={112 2},
  pages={493-500}
}
BACKGROUND & AIMS The maintenance of the telomere to a certain length is considered to be vital for cellular immortality. Recently, the presence of telomerase, an enzyme that elongates telomere length, was reported in various malignancies. The aim of this study was to characterize telomerase activity and telomere length in hepatocellular carcinoma and chronic liver diseases to facilitate better understanding and more accurate diagnosis of hepatocellular carcinoma. METHODS In tumorous and… CONTINUE READING

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