Telomerase activation: a potential key modulator for human healthspan and longevity.

@article{Boccardi2014TelomeraseAA,
  title={Telomerase activation: a potential key modulator for human healthspan and longevity.},
  author={Virginia Boccardi and Guiseppe Paolisso},
  journal={Ageing research reviews},
  year={2014},
  volume={15},
  pages={1-5}
}
The elderly population is increasing progressively. Along with this increase the number of age related diseases, such as cardiovascular, neurodegenerative diseases, metabolic impairment and cancer, is also on the rise thereby negatively impacting the burden on health care systems. Telomere shortening and dysfunction results in cellular senescence, an irreversible proliferative arrest that has been suggested to promote organismal aging and disabling age-related diseases. Given that telomerase… CONTINUE READING