Telomerase-Null Survivor Screening Identifies Novel Telomere Recombination Regulators

Abstract

Telomeres are protein-DNA structures found at the ends of linear chromosomes and are crucial for genome integrity. Telomeric DNA length is primarily maintained by the enzyme telomerase. Cells lacking telomerase will undergo senescence when telomeres become critically short. In Saccharomyces cerevisiae, a very small percentage of cells lacking telomerase can… (More)
DOI: 10.1371/journal.pgen.1003208

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Cite this paper

@inproceedings{Hu2013TelomeraseNullSS, title={Telomerase-Null Survivor Screening Identifies Novel Telomere Recombination Regulators}, author={Yan Hu and Hong-Bo Tang and Ning-ning Liu and Xia-Jing Tong and Wei Lien Dang and Yi-Min Duan and Xiao-Hong Fu and Yang Zhang and Jing Peng and Fei-Long Meng and Jin-Qiu Zhou}, booktitle={PLoS genetics}, year={2013} }