Telocytes are the common cell of origin of both PEComas and GISTs: an evidence-supported hypothesis

@inproceedings{Ardeleanu2011TelocytesAT,
  title={Telocytes are the common cell of origin of both PEComas and GISTs: an evidence-supported hypothesis},
  author={Carmen Maria Ardeleanu and Gianni Bussolati},
  booktitle={Journal of cellular and molecular medicine},
  year={2011}
}
We advance the hypothesis that the telocyte might be the cell of origin of both PEComas (perivascular epithelioid cell tumours) and GISTs (gastro-intestinal and extra-gastrointestinal stromal tumours). The hypothesis is supported by data from the literature reporting that both PEComas and GISTs, as well as telocytes, share the expression of several markers. These data were supplemented by original immunohistochemical tests on selected series. Specifically: (1) Melanoma markers (Melan A, MiTF… CONTINUE READING
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