Teleostean IL11b exhibits complementing function to IL11a and expansive involvement in antibacterial and antiviral responses.

@article{Santos2008TeleosteanIE,
  title={Teleostean IL11b exhibits complementing function to IL11a and expansive involvement in antibacterial and antiviral responses.},
  author={M. Trindade dos Santos and Motoshige Yasuike and Hidehiro Kondo and Ikuo Hirono and Takashi Aoki},
  journal={Molecular immunology},
  year={2008},
  volume={45 12},
  pages={3494-501}
}
Interleukin 11 is a class-1 helical cytokine, having the four-helix bundle structure, possessing pleiotropic characteristics involved in physiological processes including blood production, bone formation and placentation. The interleukin 11 paralogues (IL11a and IL11b) have been identified in fish with only IL11a from carp and trout have been characterized and analyzed for its expression thus far. Here, we cloned and studied the structure and expression of IL11b in Japanese flounder… CONTINUE READING
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