Telaprevir/boceprevir era: from bench to bed and back.

Abstract

Hepatitis C virus (HCV) infects approximately 200 million people worldwide. Interferon-based therapies have dominated over the past two decades. However, the overall response rates remain suboptimal. Thanks to the tremendous effort from both academia and industry, two serine protease inhibitors telaprevir and boceprevir for treating chronic hepatitis C have… (More)
DOI: 10.3748/wjg.v18.i43.6183

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