Teixobactin: A Paving Stone towards A New Class of Antibiotics?
@article{Gunjal2020TeixobactinAP, title={Teixobactin: A Paving Stone towards A New Class of Antibiotics?}, author={Vidya B. Gunjal and Ritesh P. Thakare and Sidharth Chopra and D. Srinivasa Reddy}, journal={Journal of medicinal chemistry}, year={2020} }
Antimicrobial resistance is a serious threat to human health worldwide, prompting research efforts on a massive scale in search of novel antibiotics to fill an urgent need for a remedy. Teixobactin, a macrocyclic depsipeptide natural product, isolated from uncultured bacteria (Eleftheria terrae), displayed potent activity against several Gram-positive pathogenic bacteria. The distinct pharmacological profile and interesting structural features of teixobactin with non-standard amino acid (three…
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