Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant mice

@inproceedings{Ghaffari2010TectorialMT,
  title={Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant mice},
  author={Roozbeh Ghaffari and Alexander J. Aranyosi and Guy P Richardson and D. M. Freeman},
  booktitle={Nature communications},
  year={2010}
}
Remarkable sensitivity and exquisite frequency selectivity are hallmarks of mammalian hearing, but their underlying mechanisms remain unclear. Cochlear insults and hearing disorders that decrease sensitivity also tend to broaden tuning, suggesting that these properties are linked. However, a recently developed mouse model of genetically altered hearing (Tectb(-/-)) shows decreased sensitivity and sharper frequency selectivity. In this paper, we show that the Tectb mutation reduces the spatial… CONTINUE READING

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