TectoRNA: modular assembly units for the construction of RNA nano-objects.

@article{Jaeger2001TectoRNAMA,
  title={TectoRNA: modular assembly units for the construction of RNA nano-objects.},
  author={Lutz Jaeger and E. Westhof and Neocles B Leontis},
  journal={Nucleic acids research},
  year={2001},
  volume={29 2},
  pages={455-63}
}
Structural information on complex biological RNA molecules can be exploited to design tectoRNAs or artificial modular RNA units that can self-assemble through tertiary interactions thereby forming nanoscale RNA objects. The selective interactions of hairpin tetraloops with their receptors can be used to mediate tectoRNA assembly. Here we report on the modulation of the specificity and the strength of tectoRNA assembly (in the nanomolar to micromolar range) by variation of the length of the RNA… CONTINUE READING

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