Corpus ID: 211678192

Technology dictates algorithms: Recent developments in read alignment

  title={Technology dictates algorithms: Recent developments in read alignment},
  author={M. Alser and Jeremy Rotman and K. Taraszka and Huwenbo Shi and P. I. Baykal and H. Yang and Victor Xue and S. Knyazev and B. Singer and Brunilda Balliu and David Koslicki and P. Skums and A. Zelikovsky and C. Alkan and O. Mutlu and S. Mangul},
  journal={arXiv: Genomics},
Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of genomic data in the form of nucleotide sequences or reads. Aligning reads onto reference genomes enables the identification of individual-specific genetic variants and is an essential step of the majority of genomic analysis pipelines. Aligned reads are essential… Expand
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