Technology Insight: querying the genome with microarrays—progress and hope for neurological disease

@article{Coppola2006TechnologyIQ,
  title={Technology Insight: querying the genome with microarrays—progress and hope for neurological disease},
  author={Giovanni Coppola and Daniel H. Geschwind},
  journal={Nature Clinical Practice Neurology},
  year={2006},
  volume={2},
  pages={147-158}
}
The ability to perform large-scale analysis of the genome at the level of gene sequence, gene copy number and messenger RNA transcript expression characterizes the post-genomic era. In the past decade, the microarray-based approach has emerged as one of the major tools in this area of genome biology, contributing to advances in the understanding of Mendelian and complex neurological disorders. Despite technical issues regarding design, data analysis and validation that have to be addressed in… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 99 references

A genome-wide scalable SNP genotyping assay using microarray technology

  • KL Gunderson
  • Nat Genet
  • 2005

A unique gene expression signature discriminates familial Alzheimer’s disease mutation carriers from their wild-type siblings

  • Y Nagasaka
  • Proc Natl Acad Sci USA
  • 2005
1 Excerpt

Similar Papers

Loading similar papers…