IN VITRO ANTITRYPANOSOMAL EVALUATION OF PICRO RHIZA KURROA RHIZOMES
In this study, Picrorrhiza kurroa rihzomes were cold extracted with methanolic solvent at concentrations and the meethanolic plant extract obtained was tested against Trypanosoma evansi for antitrypanosomal activity and moderate anti trypanosmal activity of MPE of P. kurrroa was observed.
Flow cytometric enumeration of parasitaemia and haematologic changes in trypanosoma-infected mice.
- BiologyActa tropica
Response of microminerals in serum of sheep infected with Trypanosoma congolense
The increase in concentrations of calcium, iron and phosphorus may suggest that they could have a role in the pathogenesis of trypanosomosis due to T. congolense.
Morphological appearance of trypanosomes in relation to drug sensitivity: comparative studies between drug-sensitive and drug-resistant Trypanosoma congolense strain in murine and bovine model
Findings preliminarily suggest a correlation between the therapeutic sensitivity and morphological appearance of T. congolense and the abundance of short-form of bloodstream trypanosomes in both mice and cattle was significantly higher in drug-resistant than drug-sensitive T. Congolenses.
ADVANCES IN PHARMACOGNOSY AND PHYTOMEDICINE
Alsever’s medium supported trypanosomes with observed anti-trypanosomal activity and could be further strengthened by (e.g. bioassay-guided purification) of P. kurroa for isolation of trypanocidal compound(s) that may lead to development of new trypanocide.
In-vitro and In-vivo Anti-trypanosomal Activity of Terminalia chebula Retz Dried Fruits
Methanolic plant extract of Terminalia chebula dried fruits possessed trypanocidal compounds and was screened against Trypanosoma evansi for trypanoidal activity, finding it to have the full potential as future trypanocide candidate.
Blood chemistry of west African dwarf goats naturally infested with sarcoptic mange superinfected with trypanosoma brucei experimentally
Blood biochemistry was monitored in Twelve West African Dwarf goats. Eight naturally infested with mange Sarcoptes scabiei var caprae and later superinfected with Trypanosoma brucei , while the other…
THERAPEUTIC EVALUATION OF METHANOLIC EXTRACT OF AGERATUM HOUSTONIONUM LEAVES AGAINST TRYPANOSOMA EVANSI
Methanolic plant extract (MPE) of Ageratum houstonionum leaves at concentrations (250-1000 μg/ml) was screened against Trypanosom aevansi forits trypanocidal activity. It was carried out on Vero…
Antitrypanosomal Effects of Brassica Oleracea (Cabbage) Fruits and Leaves
Brassica oleracea fruits and leaves demonstrated trypanocidal activity, which ranged from immobilization, reduction and to the killing of trypanosomes, which was statistical comparable to the standard drug, diminazine aceturate at concentration of 50 µg/ml at 4 h of incubation.
Preliminary Studies of Trypanocidal Activity of Embilica Officinalis Fruits (Syn: Phyllantus Emblica) -
Emblica officinalis fruits demonstrated trypanocidal activity, which ranged from immobilization, reduction and to the killing of trypanosomes, which was comparable to the standard drug, diminazine aceturate at concentration of 50 µg/ml at 4 h.