Techniques for isolation and performance of the perfused guinea pig working heart.

  • C. T. Liu
  • Published 1986 in American journal of veterinary research


This study demonstrated new approaches which enabled evaluating the work performance in both ventricles of an isolated guinea pig heart. By changing the right atrial filling pressure (RAFP, preload) from 6 to 20 mm of Hg at a constant aortic pressure (Pa, 20 mm of Hg), cardiac output, stroke volume, aortic flow, coronary flow, cardiac work, O2 consumption… (More)


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