Technique for Identifying Y Chromosomes in Human Interphase Nuclei

@article{Pearson1970TechniqueFI,
  title={Technique for Identifying Y Chromosomes in Human Interphase Nuclei},
  author={P. Pearson and Martin Bobrow and C. G. VOSA},
  journal={Nature},
  year={1970},
  volume={226},
  pages={78-80}
}
CASPERSSON et al.1,2 have reported the staining of mitotic chromosomes in various organisms using fluorescent acridine derivatives. According to Zech3, the distal portion of the human Y chromosome fluoresces brightly when stained with quinacrine mustard. Vosa4 has observed similar fluorescence using quinacrine dihydro-chloride, which is more easily obtainable. We therefore investigated the possibility of positively identifying male nuclei in interphase by virtue of this staining property of the… CONTINUE READING

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