TechnicalFactorsAffectingthe Reproducibilityof IntravesicalMouse BladderTumor ImplantationduringTherapywithBacillusCalmette- Guér/n1

@inproceedings{Amos1984TechnicalFactorsAffectingtheRI,
  title={TechnicalFactorsAffectingthe Reproducibilityof IntravesicalMouse BladderTumor ImplantationduringTherapywithBacillusCalmette- Guér/n1},
  author={Amos and Shapiro and David and Rusty Kelley and Dennis and M. Oakley and William and J. Catalona and Timothy and Lillian J. Ratliff},
  year={1984}
}
  • Amos, Shapiro, +7 authors Lillian J. Ratliff
  • Published 1984
Four methods of intravesical implantation of the transplantable mouse bladder tumor, MBT-2, and their effects on intravesical therapy with Bacillus Calmette-Guérin (BCG) were compared, and modifications which improved implantation are described. Pretreatment of the bladder with A/-methyl-A/-nitrosourea (MNU) resulted in tumor implantation in approximately two-thirds of the animals; however, all tumors penetrated the bladder wall. Using the MNU implantation procedure, intravesical BCG therapy… CONTINUE READING

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