Technical and implementation issues in using next-generation sequencing of cancers in clinical practice

@inproceedings{Ulahannan2013TechnicalAI,
  title={Technical and implementation issues in using next-generation sequencing of cancers in clinical practice},
  author={Danny Ulahannan and Michal B. Kovac and Patrick J. Mulholland and J-B Cazier and Ian P. M. Tomlinson},
  booktitle={British Journal of Cancer},
  year={2013}
}
Next-generation sequencing (NGS) of cancer genomes promises to revolutionise oncology, with the ability to design and use targeted drugs, to predict outcome and response, and to classify tumours. It is continually becoming cheaper, faster and more reliable, with the capability to identify rare yet clinically important somatic mutations. Technical challenges include sequencing samples of low quality and/or quantity, reliable identification of structural and copy number variation, and assessment… CONTINUE READING
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