Teasing out the tangles

764 VOLUME 12 | NUMBER 7 | JULY 2006 NATURE MEDICINE Figure 1 Axonal transport proceeds along microtubule tracks (blue), covered by microtubuleassociated proteins (MAPs) such as tau (tan), which are involved in correct spacing and stabilization of the tracks (lower panel). Progressive elevation of tau levels and/or hyperphosphorylation of tau (green star… (More)