Tear and mucus eotaxin-1 and eotaxin-2 in allergic keratoconjunctivitis.

  title={Tear and mucus eotaxin-1 and eotaxin-2 in allergic keratoconjunctivitis.},
  author={A. Leonardi and P. Jose and H. Zhan and V. Calder},
  volume={110 3},
  • A. Leonardi, P. Jose, +1 author V. Calder
  • Published 2003
  • Medicine
  • Ophthalmology
  • OBJECTIVE Eotaxin-1 and eotaxin-2 are potent eosinophil chemotactic and activating peptides that may be implicated in the pathogenesis of the chronic allergic eye diseases vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC). The purpose of this study was to measure these chemokines in tear and mucus samples of active-disease patients and in vitro cultured conjunctival epithelial cells and fibroblasts. DESIGN Comparative, observational case series and in vitro study… CONTINUE READING
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