Teaching electron diffraction and imaging of macromolecules.

@article{Chiu1993TeachingED,
  title={Teaching electron diffraction and imaging of macromolecules.},
  author={Wah Chiu and Michael F. Schmid and B. V. Venkataram Prasad},
  journal={Biophysical journal},
  year={1993},
  volume={64 5},
  pages={
          1610-25
        }
}
Electron microscopic analysis can be used to determine the three-dimensional structures of macromolecules at resolutions ranging between 3 and 30 A. It differs from nuclear magnetic resonance spectroscopy or x-ray crystallography in that it allows an object's Coulomb potential functions to be determined directly from images and can be used to study relatively complex macromolecular assemblies in a crystalline or noncrystalline state. Electron imaging already has provided valuable structural… CONTINUE READING

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